Imaging the Effect of Centrotemporal Spikes and Seizures on Language in Children

Inclusion Criteria for BECTS participants Diagnosis: Child has newly diagnosed BECTS according to International League Against Epilepsy (ILAE) criteria (including normal EEG background for age, at least 1 partial onset seizure, and unilateral or bilateral central/mid-temporal sharp waves with a positive horizontal dipole). Age: The child's age is between 5 years, 0 months and 13 years, 11 months at study entry. Language: The child must be a monolingual native speaker of English. Handedness : The child must be right-handed. Females: females of child bearing potential must agree to an acceptable and non-systemic form of birth control (including abstinence). Intelligence: The child must have clinician-judged normal intelligence. Academic History: The child must have an academic history of a regular education program (i.e., not in a special education class or program) without repeating grades. Parent/Guardians: * The patient's parent/guardian must be able to keep an accurate seizure record. * Informed consent from the child's parent or legal guardian. * Parents (guardians) must be able and willing to comply with instructions and study procedures. Assent: Assent from the child if age 11 years or older. Demographic characteristics: Children will be between 7 and \< 14 years old at the time of enrollment. Children of both sexes and all race/ethnicities will be enrolled. Exclusion Criteria for BECTS participants Clinical Contraindications * Children with diagnosis of Be…