Active — Not RecruitingNot Applicable

Analyzing the Composition of Tears and Blood for Discovery of Novel Signatures of Aggressive Prostate Cancer

United States75 participantsStarted 2012-01-01

Plain-language summary

The purpose of this research study is to compare profiles in the blood and tears of patients with and without prostate cancer with the goal of developing a method of separating men with aggressive and non-aggressive disease.

Who can participate

Age range35 Years – 85 Years

SexMALE

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Inclusion criteria

✓. Male, 35-85 years old
✓. Patients who present for the evaluation of an abnormal exam or test (elevated PSA, abnormal DRE, etc.)
✓. Patients who present for the evaluation of a palpable nodule or induration on prostate exam
✓. Patients who meet the requirements of Group 1, 2, or 3 of the protocol

Exclusion criteria

✕. Patient \< 35 or \> 85 years of age
✕. Concurrent eye infection or trauma, including active conjunctivitis
✕. Abnormal production of tears (too much or too little)
✕. Any other conditions the PI or staff feels will not fulfill the criteria for study entry or will place the subject in a harmful environment
✕. Atypia on prostate biopsy report

What they're measuring

Tear Sample

Timeframe: 1 day

Trial details

NCT IDNCT01514669

SponsorUniversity of Arkansas

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2027-02

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