WithdrawnNot Applicable

Intelligence Changes Following Minor Surgery

Stopped: No patients enrolled.

China0Started 2011-11

Plain-language summary

Animal studies showed that many general anesthetics might result in neuron apoptosis and neurocognitive impairment in the developing brain. However results from human studies are conflicted. In present study, the investigators examined the association between early exposure to anesthesia and surgery for minor surgery and intelligence changes in adolescence using the Wechsler Intelligence Scale for Children.

Who can participate

Age range6 Years – 16 Years

SexMALE

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. Born from 1995
✓. Male
✓. Parents or guardian agree to attend this study
✓. Undergone minor surgery (Repair of hypospadias, phimosiectomy, cryptorchidectomy or cryptorchidopexy and repair of inguinal hernia)
✓. Children who scarify the No.1 to No.3 but no experience of any surgery.
✓. Those who undergone minor surgery in Renji Hospital 4-6years ago.

Exclusion criteria

✕. Any congenital central nervous system diseases
✕. Any congenital heart diseases
✕. Any congenital dysgnosia
✕. Birth weight less than 2kg
✕. Ever been hypoxic encephalopathy when birth

What they're measuring

Wechsler Intelligence Scale for Children

Timeframe: Average 5 years after surgery

Trial details

NCT IDNCT01483313

SponsorRenJi Hospital

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2012-10

View on ClinicalTrials.gov More Hypospadia trials