The purpose of the study is to compare the concentrations of Vitamin B1 (thiamine), Vitamin B6 (pyridoxal-5-phosphate), folate, Vitamin B12 (cobalamin), Vitamin C (ascorbic acid), Vitamin A (retinol), Vitamin E (alfa-tocopherol), homocystein, uric acid, F2 8-α-isoprostane, 8-deoxyguanosine, retinoids, tau-protein and β-amyloid in spinal fluid, metabolomics, proteomics, m-RNA for DNA repair enzymes and DNA in patients who suffer from mild cognitive impairment (MCI) or mild dementia of Alzheimers type, with healthy controls. A second aim is to explore the association between vitamin and nutrient reductions, if any, and cognitive function as well as vascular score and possible changes in the MRI.
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Vitamin A
Timeframe: Up to 4 weeks after inclusion
Vitamin B1
Timeframe: Up to 4 weeks after inclusion
Vitamin B6
Timeframe: Up to 4 weeks after inclusion
Vitamin B12
Timeframe: Up to 4 weeks after inclusion
Vitamin C
Timeframe: Up to 4 weeks after inclusion
Vitamin E
Timeframe: Up to 4 weeks after inclusion