CompletedNot Applicable

Enteral Nutrition as Stress Ulcer Prophylaxis in Critically Ill Patients.

United States124 participantsStarted 2013-09

Plain-language summary

study is to determine if proton pump inhibitors plus enteral nutrition is superior to enteral nutrition alone as a stress ulcer prophylaxis strategy in critically ill patients in terms of incidence of overt and significant GI bleeding related to stress gastropathy.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age 18 years or older * Admission to the medical ICU at University of Louisville Hospital or Jewish Hospital * Expected need for mechanical ventilation \> 48 hours * No contraindication to EN within the first 24 hours after admission to the ICU Exclusion Criteria: * Evidence of active GI bleeding during current hospitalization prior to study entry * Admission to ICU with primary diagnosis of burn injury * Closed head injury or increased intracranial pressure * Partial or complete gastrectomy * Pregnancy or lactation

What they're measuring

Number of Subjects With GI Bleeding

Timeframe: Subjects will be followed from date of randomization until discharge from the ICU or cessation of Enteral Nutrition (EN) and successful initiation of oral feeds up to 100 weeks.

Trial details

NCT IDNCT01477320

SponsorMohamed Saad

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2016-07

Results submitted2017-08-17

View on ClinicalTrials.gov More Gastrointestinal Hemorrhage trials