TerminatedNot Applicable

Personalized Mean Arterial Pressure Management on Renal Function During Septic Shock

Stopped: lack of inclusions

France27 participantsStarted 2013-01

Plain-language summary

Sepsis is the most severe complication of infections. Sepsis-associated Acute kidney injury (AKI) is commonly encountered in critically ill patients and independently predicts poor outcome. Unfortunately, no drug or management strategy was able to reduce incidence of AKI. To adapt the level of mean arterial pressure according to local renal hemodynamic evaluated by renal Doppler could lead to a better renal perfusion, and then less AKI.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Any patient with septic shock may be included in the next 6 to 16h * Age \> 18 years old and \<= 80 years Exclusion Criteria: * Chronic renal failure (Baseline serum creatinine \> 120 mmol/L) * Chronic cardiac failure (Left ventricle ejection fraction \< 40%) * Pregnancy * Urinary Tract Infection * Patients with a left ventricular dysfunction ( ventricular ejection fraction \<40%)

What they're measuring

Acute kidney injury according to RIFLE score

Timeframe: at 7 days

Trial details

NCT IDNCT01473498

SponsorAssistance Publique - Hôpitaux de Paris

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2015-09

View on ClinicalTrials.gov More Septic Shock trials