CompletedNot Applicable

A Prospective Controlled Study on Treatment of Giant Cavernous Hemangiomas of the Liver

China140 participantsStarted 2011-11

Plain-language summary

In the past, the investigators often treated giant cavernous hemangiomas of the liver by hepatectomy.Recently RFA and laparoscopic hepatectomy are also available and could be applied to cure this disease.But we can't get a clear answer about their effectiveness and safety. Hence the investigators conduct this study to explore the effectiveness and efficiency of the these two methods and compare their short to mid-term outcomes.

Who can participate

Age range

18 Years – 65 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * giant cavernous hemangiomas with a diameter larger than or equal to 5 cm diagnosed by more than one imaging modalities * age between 18 years to 65 years * without gender restriction * PLT account more than 50 e9 * without abnormal of liver function test * with substantial evidence of growing size than before * symptom associated cavernous hemangiomas * with a strong desire of the patients for the treatment Exclusion Criteria: * pregnant women * abnormal of liver function or coagulation dysfunction and/or concurrent with sever cardiac or pulmonary disorders * patient with a poor condition that can't bear the approach of either RFA or laparoscopic hepatectomy * tumor size more than 20cm

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

disappearance rate of disease

Timeframe: 1 month

Trial details

NCT IDNCT01471080

SponsorSouthwest Hospital, China

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2013-10

View on ClinicalTrials.gov More Laparoscopic Hepatectomy trials