TerminatedNot Applicable

The Effect of Intravenous Lidocaine on Post-extubation Laryngospasm

Stopped: Patient Safety Concerns

Saudi Arabia134 participantsStarted 2012-01

Plain-language summary

In the literature, we found no randomized clinical trials addressing the using of IV lidocaine as prophylaxis for postoperative laryngospasm among adults. The aim of this study was to assess the effects of IV lidocaine on the incidence of postoperative laryngospasm of adults patients.

Who can participate

Age range18 Years – 60 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * American Society of Anesthesia score are I or II * Undergo for laparoscopic cholecystectomy Exclusion Criteria: * Patient's refusal * History of upper respiratory tract infection (URTI) within 2 weeks * Persistent type of hyper-reactive airway or asthma * History of airway surgery * History of gastro-esophageal reflex disease (GERD) * Currently receiving sedating or analgesic medication * Currently receiving the following medications: * Fluvoxamine * Erythromycin and Itraconazole * β -blocker or Cimetidine * History of Lidocaine Allergy * History of epilepsy disorder * Pregnant or breastfeeding women * History of Heavy Smoking ( a smoker with a daily cigarettes consumption of more than 20 pieces * History of increased salivation by a disease or medication * History of difficult intubation * Two or more attempts of intubation

What they're measuring

Number of Patients With Laryngospasm Postoperatively

Timeframe: within first 15 minutes post-dose

Trial details

NCT IDNCT01445847

SponsorKing Saud University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2012-04

Results submitted2012-06-11

View on ClinicalTrials.gov More Laryngospasm trials