TerminatedNot Applicable

The Effect of Intravenous Lidocaine on Post-extubation Laryngospasm

Stopped: Patient Safety Concerns

Saudi Arabia134 participantsStarted 2012-01

Plain-language summary

In the literature, we found no randomized clinical trials addressing the using of IV lidocaine as prophylaxis for postoperative laryngospasm among adults. The aim of this study was to assess the effects of IV lidocaine on the incidence of postoperative laryngospasm of adults patients.

Who can participate

Age range

18 Years – 60 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * American Society of Anesthesia score are I or II * Undergo for laparoscopic cholecystectomy Exclusion Criteria: * Patient's refusal * History of upper respiratory tract infection (URTI) within 2 weeks * Persistent type of hyper-reactive airway or asthma * History of airway surgery * History of gastro-esophageal reflex disease (GERD) * Currently receiving sedating or analgesic medication * Currently receiving the following medications: * Fluvoxamine * Erythromycin and Itraconazole * β -blocker or Cimetidine * History of Lidocaine Allergy * History of epilepsy disorder * Pregnant or breastfeeding women * History of Heavy Smoking ( a smoker with a daily cigarettes consumption of more than 20 pieces * History of increased salivation by a disease or medication * History of difficult intubation * Two or more attempts of intubation

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Number of Patients With Laryngospasm Postoperatively

Timeframe: within first 15 minutes post-dose

Trial details

NCT IDNCT01445847

SponsorKing Saud University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2012-04

Results submitted2012-06-11

View on ClinicalTrials.gov More Laryngospasm trials

Who can participate

Age range

18 Years – 60 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.