CompletedPhase 2

Flavanols and Skin Photo Protection: a Clinical Trial

Canada78 participantsStarted 2011-06

Plain-language summary

As flavanols have antioxidants, anti-inflammatory and anti-DNA damaging effects and may increase microcirculation in skin, the purpose of the study is to investigate the chronic effect of flavanol-rich chocolate as an effective strategy to protect against the harmful effect of ultraviolet (UV) radiation.

Who can participate

Age range20 Years – 65 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Non-smoking women between the ages of 20 and 65 years. * Normal skin of type I and II as decried by Fitzpatrick classification. Exclusion Criteria: * Pregnancy and breast feeding. * Photo sensibility: history of skin cancers, photosensitizing medication. * Sun bed use or sunbathing in the previous 3 months. * Use of supplements or natural health products (fish oils, coenzyme Q10, garlic, lycopene, beta carotene). * Allergy or intolerance to nuts or chocolate.

What they're measuring

Change in Minimal erythema dose

Timeframe: within the first 12 weeks of chocolate intake and 3 weeks later after end of chocolate consumption

Trial details

NCT IDNCT01444625

SponsorLaval University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2012-09

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