Safety and Efficacy Study of BT086 to Evaluate Adjunctive Therapy in sCAP

Inclusion Criteria: * Written informed consent: * given by the patient or * a legal/authorised representative of the patient or * a waiver for written informed consent due to emergency situation, in compliance with all local legal requirements. * Male or female patients aged 18 years or older * Patient receiving adequate antibiotic treatment for pneumonia * Prior to endotracheal ventilation and therapy, the patient must have at least one of the following two signs of inflammation: * Fever/Hypothermia Fever defined as an oral, tympanic, oesophageal or vesical temperature of \>38°C, tympanic temperature of \>38°C or rectal temperature of \>38.5°C, or hypothermia (rectal temperature \<35.5°C) (measurement with temperature probe or device) or * White blood cell (WBC) count \>10,000/mm³ or WBC \<4,500/mm³ * Patient must have at least one of the following signs and symptoms of pneumonia: * New or increased cough * Production of purulent sputum or change in sputum characteristics * Dyspnoea or tachypnoea (respiratory rate \>20 breaths/minute) * Pleuritic chest pain * Auscultatory findings on pulmonary examination of rales and/or crackles and/or evidence of pulmonary consolidation (e.g. dullness on percussion, bronchial breath sounds, or egophony) * Radiological (or other imaging technique) evidence of (an) infiltrate(s) consistent with bacterial pneumonia * Pneumonia has been acquired outside the hospital. In hospital-admitted patients, pneumonia has been dia…