Evaluation of 70% Ethanol Lock Solution to Prevent Catheter Related Blood Stream Infections in Pediatric Patients

Inclusion Criteria: * Signed informed consent/assent and willingness to adhere to protocol * Intestinal rehabilitation patients with documented short bowel syndrome * Age: newborn to 19 years of age * Indwelling tunneled venous catheter placed for the purpose of total parenteral nutrition/IV fluids, with a 2 hour or longer window out of 24 hours for ethanol lock instillation * No history of alcohol abuse * No history of hypersensitivity to ethanol * No history or documented active seizure disorder Exclusion Criteria: * Parent/guardian unwilling to sign consent * Active bacterial infection * Non-tunneled, non-permanent catheter (triple lumen or PICC) * Pre-existing condition that would prevent enrollment as determined by each patients' physician * Inability to adhere to protocol