The Efficacity of Hemodiafiltration Versus Hemofiltration for Renal Insufficiency During Intensiv… (NCT01403220) | Clinical Trial Compass
CompletedNot Applicable
The Efficacity of Hemodiafiltration Versus Hemofiltration for Renal Insufficiency During Intensive Care
France163 participantsStarted 2012-04
Plain-language summary
The primary objective of this study is to compare the efficacity of hemodiafiltration and hemofiltration for decreasing plasma urea at 12h among intensive care patients. Secondary objectives include comparing urea clearance, filter duration, and %down-time, between the two techniques.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* According to RIFLE score, patient is stage 'F'
* The patient must be insured or beneficiary of a health insurance plan
* The patient meets at least one of the following criteria:
* metabolic acidosis (pH \< 7.2), excluding keto-acidosis
* plasma urea \> 25 mmol/l
* hyper-hydration is not controlled by diuretics
Exclusion Criteria:
* Chronic, terminal renal insufficiency with dialysis
* The patient is under judicial protection, under tutorship or curatorship
* Suspect hyperkaliemia (Kaliemia \> 6.5 mmol/l with electrocardiographic effects)
* Intoxications treated via dialysis
* Pregnant, lactating, parturient women
* Medical indication for localized citrate anticoagulation
* dialysis of less than 12 h
* patient or representative refuses to participate
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Proportion of dialysis sequences for which the rate of plasma urea reduction > 60%.