CompletedNot Applicable

Glutathione and Health With Post-Polio Syndrome

United States20 participantsStarted 2011-08

Plain-language summary

In this study, people who have symptoms of post polio will take oral glutathione supplements for three months. Their levels of fatigue, physical activity and sleep efficiency will be assessed.

Who can participate

Age range

50 Years – 65 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Ability to walk 100 feet with usual assistive devices (ex. cane or walker) * Having a function score of 18-32 when tested with the IPPS (Index of Post- Polio Sequelae). This will include people with post-polio symptoms in a very specific range of severity. Exclusion Criteria: * Having another serious medical condition (cancer, multiple sclerosis, etc.)or inflammatory disease (ie., lupus) * Currently taking glutathione or other antioxidants

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

PROMIS (Patient Reported Outcomes Measurement Information System) Physical Functioning

Timeframe: Baseline, 1 month, 2 months and 3 months

Sleep Efficiency

Timeframe: Baseline, 1 month, 2 months and 3 months

Steps Per Day

Timeframe: Baseline, 1 month, 2 months and 3 months

PROMIS (Patient Reported Outcomes Measurement Information System) Fatigue

Timeframe: Baseline, 1 month, 2 months and 3 months

Trial details

NCT IDNCT01402570

SponsorUniversity of Michigan

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2013-04

Results submitted2016-01-22

View on ClinicalTrials.gov More Post-polio Syndrome trials

Who can participate

Age range

50 Years – 65 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

PROMIS (Patient Reported Outcomes Measurement Information System) Physical Functioning

Timeframe: Baseline, 1 month, 2 months and 3 months

Sleep Efficiency

Timeframe: Baseline, 1 month, 2 months and 3 months

Steps Per Day

Timeframe: Baseline, 1 month, 2 months and 3 months

PROMIS (Patient Reported Outcomes Measurement Information System) Fatigue

Timeframe: Baseline, 1 month, 2 months and 3 months