CompletedNot Applicable

Developing Methods for Completing Future Satiety Studies

Canada20 participantsStarted 2013-02

Plain-language summary

Satiety is defined as the inhibition of eating, as a consequence of fullness after consuming food. Being able to effectively measure satiety is an important concept that has implications in the treatment and prevention of overweight and obesity. Increasing post-meal satiety is recognized a useful strategy for weight management. Recently, the category of foods marketed as having satiating effects has seen significant growth and this trend is expected to continue. The purpose of this project is to develop and validate methods for assessing the degree of satiety induced by foods and natural health products using commercially available food products. This trial will examine the effects of a commercially available yogurt (containing added protein and fibre) on self-reported satiety and hunger, as well as food intake in both controlled and uncontrolled settings.

Who can participate

Age range

20 Years – 35 Years

Sex

FEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Healthy women with regular hormonal contraceptive use, aged between 20 and 35 years * BMI of 20.0-24.9 kg/m2 * Regular yogurt consumers (i.e. \> 3 servings per week) Exclusion Criteria: * Taking any regular medications or herbal supplements other than a multivitamin or folic acid supplement. * History of cardiovascular disease (including hypertension), diabetes, hypoglycemia, gum disease or any other medical condition * Vegans or vegetarians who exclude dairy products * Milk allergies or any other food allergies * Anyone with known anaphylactic allergic reactions, food or otherwise * Dislike or unwillingness to consume study foods * Gastrointestinal disease or disorders, including Celiac disease, lactose intolerance, irritable bowel syndrome, etc. * BMI \<20.0 or \> 25.0 kg/m2 * Current participation in diet/weight-loss programs and/or changes of \> 5 kg body weight within the past 6 months * Unusual dietary patterns (i.e. routinely skipping breakfast or other meals) * Unusual sleep patterns (i.e. shift workers) * High habitual intake of caffeinated beverages or alcohol * Restrained or disinhibited eaters, defined by the Three Factor Eating Questionnaire * Smokers

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Self-reported ratings of satiety

Timeframe: Outcome measures will be assessed at fasting (0 min) and postprandially (every 30 min) for 3 hours.

Trial details

NCT IDNCT01379911

SponsorUniversity of Guelph

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2015-10

View on ClinicalTrials.gov More Lack of Satiety trials