CompletedNot Applicable

Clearance Of Mucus In Stents (COMIS)

United States43 participantsStarted 2011-06-16

Plain-language summary

The goal of this clinical research study is to compare the effects of sodium bicarbonate to normal saline when used for clearing mucus blockage in patients with airway stents.

Who can participate

Age range18 Years

SexALL

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Inclusion criteria

✓. Adult patients (\>/= 18 years) with airway stents undergoing bronchoscopy.
✓. Patients previously enrolled, but excluded as no stent lumen obstruction from mucus retention identified at earlier enrollment (hence excluded at that enrollment) .

Exclusion criteria

✕. Patients with history of allergy or adverse reactions to sodium bicarbonate or normal saline.
✕. Patients refusing to sign informed written consent for participation in research.
✕. Patients with no stent lumen occlusion from mucus impaction as determined at the time of the initial visual bronchoscopic assessment.
✕. Previously enrolled patients who completed this protocol.

What they're measuring

Percentage of obstruction resolution as Good or Excellent

Timeframe: Baseline to 7 days

Trial details

NCT IDNCT01370278

SponsorM.D. Anderson Cancer Center

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-08-23

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