TerminatedPhase 4

Effect of Ketamine on Postoperative Clinical Outcomes

Stopped: recruitment failure

United States21 participantsStarted 2011-05

Plain-language summary

The purpose of this research is to evaluate the effectiveness of ketamine as an analgesic adjuvant in decreasing the narcotic (opioids) analgesics during surgery, on pain management and on the later recovery after surgery in patients undergoing colorectal surgery.

Who can participate

Age range18 Years – 80 Years

SexALL

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Inclusion criteria

✓. Patients scheduled to undergo small and/or large partial bowel resection via laparotomy or laparoscopy
✓. Willingness and ability to sign an informed consent document
✓. No allergies to anesthetic or analgesic medications
✓. 18 - 80 years of age
✓. American Society of Anesthesiologists (ASA) Class I - III adults of either sex

Exclusion criteria

✕. Inability to comprehend the pain assessment tools
✕. Patients with known allergy, hypersensitivity or contraindications to anesthetic or analgesic medications
✕. Patients with clinically-significant heart disease including arrhythmias and significant hypertension, brain aneurysms, prior history of cerebral vascular accident (CVA), or chronic renal insufficiency
✕. Prior abdominal surgery
✕. History of abdominal carcinomatosis
✕. History of radiation enteritis;
✕. Patients with history of hepatic, renal, cardiac failure, organ transplant, or diabetes
✕. Patients with seizures

What they're measuring

Number of Participants With Opioid Consumption

Timeframe: 1 day

Trial details

NCT IDNCT01365195

SponsorCedars-Sinai Medical Center

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2014-12

Results submitted2022-01-17

View on ClinicalTrials.gov More Colorectal Surgery trials