CompletedNot Applicable

Biomarkers in Samples From Young Patients With Neuroblastoma

20 participantsStarted 2011-05

Plain-language summary

RATIONALE: Studying samples of tissue and bone marrow from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. PURPOSE: This research study studies biomarkers in samples from young patients with neuroblastoma.

Who can participate

Age range120 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

DISEASE CHARACTERISTICS: * Diagnosed with neuroblastoma * With or without N-myc amplification * Primary tumor samples as frozen tissue in liquid nitrogen or -80 degrees C * Bone marrow samples from high-risk patients as peripheral blood mononuclear cells (PBMC) that have been cryopreserved with DMSO as viable cells to be used for flow cytometry or slides of bone marrow that can be used for immunohistochemistry PATIENT CHARACTERISTICS: * Not specified PRIOR CONCURRENT THERAPY: * Not specified

What they're measuring

ROR1 is expressed on the surface of neuroblastoma cells and constitutes a suitable target for mAb therapy

Trial details

NCT IDNCT01358604

SponsorChildren's Oncology Group

Sponsor typeNETWORK

Study typeOBSERVATIONAL

Primary completion2016-04

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