Neurogenic Detrusor Overactivity Following Spinal Cord Injury or Multiple Sclerosis

Inclusion Criteria: * Subject, family member or care giver was willing and able to perform clean intermittent catheterisation (CIC) for the duration of the study * Inadequate response or refractory to anticholinergic medication * Botulinum Toxin naive for intradetrusor injections and with no previous treatment with Botulinum Toxin of any type, within 3 months prior to study entry for any other condition * Have a minimum of 2 incontinences per day calculated as the average daily incontinence episode frequency (IEF) over the 3 days preceding the baseline visit Exclusion Criteria: * Significant Baseline renal and/or urinary tract pathology * Previous treatment with any endovesical pharmacology agent including detrusor Botulinum Toxin injection