CompletedNot Applicable

Biomarker Development in Sturge-Weber Syndrome

United States40 participantsStarted 2010-07

Plain-language summary

This is a study of 40 individuals with Sturge-Weber Syndrome (SWS) brain and/or eye involvement. It will examine the test-retest reliability of the following clinical tests: 1. Quantitative EEG 2. Transcranial Doppler 3. Medical Rehabilitation Scales 4. Optical Coherence Tomography

Who can participate

Age range6 Months – 21 Years

SexALL

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Inclusion criteria

✓. Individuals with SWS and brain involvement (Aims 1-3): for the purposes of this study SWS brain involvement is defined as having shown on MRI imaging evidence of the typical vascular malformation which includes the following: leptomeningeal angioma, choroid plexus glomus, and associated venous angioma/malformation.
✓. Individuals with SWS and eye involvement (Aim 4): for the purposes of this study SWS eye involvement is defined as individuals with a port-wine birthmark in the V1 dermatomal distribution
✓. Able (or parents able) to provide informed consent
✓. Able to cooperate with tests
✓. Age 6 months to 21 years (Aims 1-3 only)

What they're measuring

Primary outcome

Timeframe: 2 years

Trial details

NCT IDNCT01345305

SponsorHugo W. Moser Research Institute at Kennedy Krieger, Inc.

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2012-11

View on ClinicalTrials.gov More Sturge-Weber Syndrome trials