UnknownPhase 2

Airway Pressure Release Ventilation (APRV) Versus AC/VC Conventional Ventilation

United States246 participantsStarted 2011-10

Plain-language summary

APRV mode of ventilation will result in an improved partial pressure of arterial oxygenation/ fraction of inspired oxygen (P/F ratio) on day 3 of mechanical ventilation. Sub hypotheses: APRV will be associated with a reduced amount of sedation used during the ICU stay in patients with respiratory failure. APRV will be associated with a reduction in the amount of vasoactive medication used for blood pressure support in patients with respiratory failure.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Hypoxemic respiratory failure requiring mechanical ventilation for \>24 hours. Exclusion Criteria: * Age under 18 * Severe chronic obstructive lung disease * Patients in whom the only indication for mechanical ventilation is airway protection from poor neurological status.

What they're measuring

P/F Ratio on Day 3 of Mechanical Ventilation

Timeframe: Day 3

Trial details

NCT IDNCT01339533

SponsorIntermountain Health Care, Inc.

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2015-12

Contact for this trial

Eliotte Hirshberg, MD

801-232-9120 ellie.hirshberg@imail.org

View on ClinicalTrials.gov More Respiratory Failure trials