CompletedNot Applicable

HPV Prevalence in the Mouth and Oropharynx of the Tonsillectomy Population

United Kingdom937 participantsStarted 2013-03

Plain-language summary

The principal aim of this study is to provide vital current data on the prevalence, distribution and natural history of Human Papilloma Virus (HPV) infection in the mouth. This data is an essential requirement for the assessment, development and evaluation of cost effectiveness of prophylactic vaccination and screening programmes.

Who can participate

Age range65 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. Subjects undergoing tonsillectomy for non cancer reasons including operations for: recurrent tonsillitis, asymmetric tonsils, snoring surgery or obstructive sleep apnoea
✓. Age - 0 to 65 years
✓. Subject or legal guardian has given informed written consent

Exclusion criteria

✕. Subjects undergoing adenoidectomy alone with no tonsillectomy
✕. Subjects with previous oropharyngeal cancer or oral cancer, or any other head and neck cancer such as nasopharyngeal or laryngeal cancer that is currently undergoing or has previously been diagnosed or treated
✕. Learning disability preventing an adult over 16 years old from giving their own consent

What they're measuring

Occurrence of HPV in tonsils and in oral scrape sample

Timeframe: 36 months

Trial details

NCT IDNCT01330147

SponsorUniversity of Birmingham

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2015-09-28

View on ClinicalTrials.gov More Chronic Tonsillitis trials