CompletedNot Applicable

Light Sensitization Study

United States32 participantsStarted 2010-10

Plain-language summary

Circadian rhythm disorders are a class of sleep disorders characterized by misalignment between the timing of sleep and the timing of rhythms driven by the biological clock. Light therapy can effectively treat these disorders, but the intensity and duration of light exposure required to do so has limited its practical use. In this study the investigators will test whether pre-exposure to dim light may enhance the response of the circadian system to light therapy. If so, this could result in shorter treatments that would have greater practical applications.

Who can participate

Age range21 Years – 30 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * healthy adults with conventional and regular sleep-wake timing * non-smokers * completion of medical, psychological, ophthalmological, and sleep screening tests * able to spend 13 consecutive days/nights in the laboratory Exclusion Criteria: * history of neurological or psychiatric disorder * history of eye injury, eye surgery, or visual disorder (corrective lenses are acceptable) * history of sleep disorder or regular use of sleep-promoting medication * current prescription, herbal, or over-the-counter medication use (oral contraceptives are acceptable)

What they're measuring

circadian phase timing

Timeframe: During inpatient study, on days 6-7 and 11-12

Trial details

NCT IDNCT01327040

SponsorBrigham and Women's Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2015-12

View on ClinicalTrials.gov More Chronobiology Disorders trials