UnknownNot Applicable

The Response of Intraocular Pressure to Systemic Hypercapnia and Hyperoxia

Canada14 participantsStarted 2011-08

Plain-language summary

The purpose of this study is to determine how intraocular pressure responds to changes in the levels of carbon dioxide or oxygen that a healthy individual inspires.

Who can participate

Age range

18 Years – 30 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age range 18-30 years old * Visual acuity of 20/20 or better Exclusion Criteria: * Refractive error \>±6.00 DS and/or ± 2.00 DC * History or presence of ocular disease * Family history of diabetes or glaucoma * History of intraocular or refractive surgery * Nursing or pregnant women * History of clinically diagnosed endocrine disease * History of vascular disease, cardiovascular disease, or any treated respiratory disorders (seasonal asthma excluded from this so long as subject not taking Rx at the time) * History of systemic hypertension * Habitual smoking * Use of medications that affect blood flow

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Intraocular pressure

Timeframe: Intraocular pressure will be measured during the study visit, ten minutes into each of the seven inhaled gas provocation stages

Trial details

NCT IDNCT01325285

SponsorUniversity of Toronto

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2011-09

Contact for this trial

Alanna Adleman, BSc

416-603-5694 aadleman@uhnresearch.ca

View on ClinicalTrials.gov More Intraocular Pressure trials

Who can participate

Age range

18 Years – 30 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.