TerminatedNot Applicable

Video-Assisted Thoracoscopic Pulmonary Vein Isolation Versus Percutaneous Catheter Ablation in Atrial Fibrillation Trial

Stopped: Inclusion rate insufficient

Netherlands77 participantsStarted 2010-09

Plain-language summary

Recent studies demonstrated that radiofrequency isolation of the pulmonary veins (PVI) and surgically video assisted thorascopic pulmonary vein isolation (VATS-PVI) are acceptable or even superior alternatives to antiarrhythmic drug therapy in patients with symptomatically paroxysmal atrial fibrillation (AF). However, data comparing effectiveness in both interventions are limited. The investigators want to compare the effectiveness of PVI and VATS-PVI. Secondary objectives are to compare the duration of hospitalization, quality of Life, cost and to compare the satisfaction of the patients.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients \> 18 years of age * Documented, symptomatic, episodes of paroxysmal or persistent AF * During the last 6 months patients must have at least 2 documented episodes of AF, despite the use of at least 1 anti arrhythmic drug. * Able of providing informed consent Exclusion Criteria: * Pregnancy * Unwillingness to use or contra-indications for vitamin K antagonists * Severely enlarged left atrium (\>50 mm) on echocardiography * Prior AF ablation or AF surgery * Intracardiac thrombus * Prior heart surgery or pulmonary disease hampering thoracoscopic surgery

What they're measuring

Recurrence of AF

Timeframe: one year

Trial details

NCT IDNCT01319747

SponsorMedisch Spectrum Twente

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2013-11

View on ClinicalTrials.gov More Atrial Fibrillation trials