WithdrawnPhase 4

A New Nasopharyngeal pH Probe for Diagnosis of Laryngopharyngeal Reflux

Stopped: Difficulty recruiting patients due to logistics

United States0Started 2010-01

Plain-language summary

The purpose of this study is to evaluate the utility of a minimally invasive nasopharyngeal pH probe for the diagnosis of laryngopharyngeal reflux (LPR) in children with airway compromise; to determine whether it is comparable to the gold standard esophageal pH probe in identifying LPR in this population; and to correlate results of pH testing with validated questionnaires. Our hypothesis is that a nasopharyngeal pH probe is equivalent to an esophageal probe in identifying laryngopharyngeal reflux.

Who can participate

Age range1 Month – 17 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * History of airway compromise * Undergoing microlaryngoscopy, bronchoscopy, esophagoscopy, and esophageal pH probe placement at CHOP Exclusion Criteria: * Patients not undergoing esophageal pH probe placement * Neonates under 1 month of age * Adults over 18 years of age or older.

What they're measuring

nasopharyngeal pH

Timeframe: 24 hours

Trial details

NCT IDNCT01308502

SponsorChildren's Hospital of Philadelphia

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2012-01

View on ClinicalTrials.gov More Laryngopharyngeal Reflux trials