CompletedPhase 3

New Adjuvant Chemotherapy of Asymptomatic Resectable Primary Lesion With Unresectable Liver-limited Metastases

China320 participantsStarted 2012-06

Plain-language summary

To evaluate the survival benefit of pre-operation chemotherapy of primary tumor tesection (PTR) compared upfront PTR for colorectal cancer (CRC) patients with an asymptomatic resectable primary tumor and synchronous unresectable liver-limited metastases with conversion therapy intent.

Who can participate

Age range18 Years – 75 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * age between 18 - 75 years old * colorectal adenocarcinoma pathologically * without any chemotherapy or radiotherapy * unresectable liver metastasis and without other metastasis * resectable colorectal cancer * suitable for chemotherapy * agreed by patients Exclusion Criteria: * age below 18 years old or greater than 75 years old * haven't pathological diagnosis of colorectal adenocarcinoma * with any chemotherapy or radiotherapy * resectable liver metastasis or without other metastasis * unresectable colorectal cancer * unsuitable for chemotherapy * not agreed by patients

What they're measuring

Progression-free survival

Timeframe: Up to 3 years

Trial details

NCT IDNCT01307878

SponsorFudan University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2021-06

View on ClinicalTrials.gov More Colorectal Neoplasms trials