Supersaturated Calcium Phosphate Rinse in Preventing Oral Mucositis in Young Patients Undergoing Autologous or Donor Stem Cell Transplant

Inclusion Criteria: * Patients undergoing myeloablative autologous or allogeneic hematopoietic stem cell transplantation (HSCT) for any indication * One or more of the following donor stem cell sources (autologous or allogeneic): * Bone marrow * Placental blood (umbilical cord blood) * Cytokine-mobilized peripheral blood * Patients eligible for allogeneic HSCT must have one of the following types of donor stem cells: * Human leukocyte antigen (HLA)-matched sibling or parent * Partially matched family donor (mismatched for a single HLA locus \[Class I\]) * Fully matched unrelated marrow or peripheral blood stem cell donor * HLA-matched or partially mismatched (at least 4 of 6 match) cord blood (Class I or II) * Patients expecting to receive any type of myeloablative HSCT conditioning regimen are eligible * No non-myeloablative or reduced-intensity conditioning regimens * Eligible patients must not have received palifermin within 30 days prior to enrollment * Eligible patients must not have received prior treatment with Caphosol Exclusion Criteria: * Females of childbearing potential must have a negative pregnancy test; patients must agree to use an effective birth control method; lactating patients must agree not to nurse a child while on this trial