CompletedPhase 2

The Effect of Dexmedetomidine on Hemodynamic Response During Double Lumen Endotracheal Intubation

Thailand60 participantsStarted 2011-03

Plain-language summary

The purpose of this study is to evaluate the effect of dexmedetomidine on hemodynamic responses during laryngoscopy and double lumen endotracheal intubation and assess the adverse effect related to complications of dexmedetomidine.

Who can participate

Age range18 Years – 65 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * ASA Physical Status I-III * Undergoing Elective Thoracotomy or Thoracoscopy * Required Left Sided-double Lumen Endotracheal Intubation Exclusion Criteria: * Patients with bradycardia (heart rate \< 50 beat per minute) or heart block * Suspected of Difficult Intubation * Patients Who Are at Risk for Rapid Change of Hemodynamics * Allergic to Dexmedetomidine * Hepatic or Renal Impairment (Preoperative Serum Creatinine \> 1.5 mg/dl) * Pregnancy

What they're measuring

change in systolic blood pressure

Timeframe: (day 1) before induction, before intubation and every minute for the first 10 minutes after endotracheal intubation

change in diastolic blood pressure

Timeframe: (day 1) before induction, before intubation and every minute for the first 10 minutes after endotracheal intubation

change in mean arterial pressure

Timeframe: (day 1) before induction, before intubation and every minute for the first 10 minutes after endotracheal intubation

change in heart rate

Timeframe: (day 1) before induction, before intubation and every minute for the first 10 minutes after endotracheal intubation

Trial details

NCT IDNCT01289769

SponsorChiang Mai University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2011-12

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