CompletedPhase 3

Comparative Validation of the Triptorelin Test for the Diagnosis of CPP in Girls

Argentina46 participantsStarted 2009-12

Plain-language summary

The aim of the study is to determine the specificity, sensitivity and diagnostic efficiency of the Triptorelin Test in the assessment of CPP compared to GnRH test as gold standard. Hypothesis: Aqueous Triptorelin Acetate is so efficient as GnRH to CPP assessment. Study population are girls with suspicious clinical features of precocious puberty

Who can participate

Age range3 Years – 8 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * premature thelarche and/or * accelerated growth velocity (above 90 percentile) * advanced bone age at least 1.5 year in relation to chronological age. Exclusion Criteria: * contact with sources of exogenous estrogens in the last four months previous to evaluation, * suspicion of peripheral precocious puberty, * previous central nervous system illness or suspicion of organic central precocious puberty.

What they're measuring

Timeframe: 3 hs

Estradiol

Timeframe: 24 hs

Trial details

NCT IDNCT01278290

SponsorHospital de Niños R. Gutierrez de Buenos Aires

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2011-06

View on ClinicalTrials.gov More Central Precocious Puberty trials