CompletedNot Applicable

Effects of Fructan Prebiotics on the Intestinal Microbiota

Canada28 participantsStarted 2011-01

Plain-language summary

Prebiotics are carbohydrate polymers believed to improve health by stimulating beneficial gastrointestinal microbial populations. Prebiotic health claims are currently not permitted in Canada due to a lack of validating scientific data. Currently, Health Canada considers 'prebiotic' to imply a health benefit that must be substantiated. Our goal is to conduct a human clinical trial to define the impacts of fructans on the colonic microbiome as well as the physiological, psychological and immunological effects on the host.

Who can participate

Age range18 Years – 50 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age: 18 - 50 years * General good health * Participant understands the study procedures and provides informed consent (signed) to participate and authorizes the release of relevant protected health information to the study investigators Exclusion Criteria: * History or presence of GI disorders (Irritable bowel syndrome, colitis, Crohn's disease, colon cancer or polyps) * Recent use of antibiotics * Regular use of high inulin containing food products. * Known intolerance or sensitivity to any ingredients in the study product. * BMI \>30

What they're measuring

Changes in gut microbiota

Timeframe: 28 days

Changes in Immunological Status

Timeframe: 28 days

Trial details

NCT IDNCT01277445

SponsorDan Ramdath

Sponsor typeOTHER_GOV

Study typeINTERVENTIONAL

Primary completion2011-03

View on ClinicalTrials.gov More Study Focus is to Define the Usual Gut Microbiota Following Prebiotic Feeding trials