CompletedNot Applicable

Trial of Alternating Current Stimulation in Optic Neuropathy

Germany22 participantsStarted 2006-11

Plain-language summary

Non-invasive brain stimulation can increase cortical excitability in the visual system, but it is not known if this is of clinical value. The investigators now assessed if repetitive, transcranial alternating current stimulation (rtACS) can improve visual field size in patients with optic nerve damage. The investigators hypothesized that rtACS would improve visual functions within the defective visual field sectors of the visual field (primary outcome measure).

Who can participate

Age range18 Years – 70 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria * patients with optic nerve lesion * stable visual field defect with residual vision * lesion age at least 6 months Exclusion Criteria * heart pacemakers and any metal artefacts in head and truncus * epileptic seizure within the last 3 years * photosensitive epilepsy as determined by EEG * mental diseases (schizophrenia etc.) * unstable diabetes, diabetes causing diabetic retinopathy * macular degeneration, maculopathy with decimal visual acuity below 0.4 * high blood pressure * instable or high level of intraocular pressure (i.e. \>27 mmHg) * presence of an un-operated tumor anywhere in the body * total blindness * primary or secondary glaucoma * pathological nystagmus

What they're measuring

Detection Accuracy (DA) Change in Percent Over Baseline Within Defective Visual Field Sectors

Timeframe: Outcome measures were assessed at initial diagnostics (baseline) and after 10 days stimulation at post diagnostics

Trial details

NCT IDNCT01270126

SponsorUniversity of Magdeburg

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2010-12

Results submitted2013-06-19

View on ClinicalTrials.gov More Optic Nerve Diseases trials