WithdrawnPhase 2

Trial of 70% Ethanol Versus Heparin to Reduce the Rate of Central Line Infections in Children With Short Bowel Syndrome

Stopped: No participants. IND denied by FDA.

United States0Started 2011-02

Plain-language summary

This study is designed to determine if the use of 70% ethanol lock solution in central lines decreases the rate of central line infections in children with short bowel syndrome. While ethanol locks have been used safely in children, there has been no published research to date that clearly shows it is of definite benefit in this group of patients.

Who can participate

Age range3 Months

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age \>3 months * Intestinal failure patients * Silicone catheter for the administration of parenteral nutrition Exclusion Criteria: * Age \< 3 months * Weight \< 5 kg * Documented allergy to ethanol * Evidence of tunnel site infection * Patients receiving continuous renal replacement therapy * Concomitant use of metronidazole

What they're measuring

Catheter associated blood stream infection (CABSI).

Timeframe: Number of infections reported per 1000 catheter days.

Trial details

NCT IDNCT01263574

SponsorBoston Children's Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2012-06

View on ClinicalTrials.gov More Catheter Related Infections trials