TerminatedNot Applicable

Post-op Treatment With Hyaluronic Acid Injections

Stopped: Insurance now covers post-op HA injections, drastically decreasing enrollment.

United States34 participantsStarted 2010-09

Plain-language summary

This study will look at patients with post-operative treatment of a meniscal tear or degenerative joint disease (degenerative arthritis). They will be randomized into one of three groups: Euflexxa injection, saline (placebo) injection, or no injection. Those who are randomized into the injection group will receive a series of three injections (one a week for 3 weeks), then a "booster" injection at 6 months post-op. Several questionnaires will be given after the first set of injections, then again at a one year follow-up. The hypothesis is that patients receiving hyaluronic acid injections will have better pain and function scores as compared with placebo and no further treatment at all time points.

Who can participate

Age range40 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients in post-op stage of treatment for meniscal tears or chondropathy/DJD * Over 40 years of age * A daily knee pain above 20mm on a 100mm visual analogue scale Exclusion Criteria: * Previous recipient of viscosupplementation injections * Had rheumatoid arthritis or other inflammatory arthritis * Had intra-articular steroid injections within the previous 2 months * Invasive knee procedures within the past 6 months * Contraindications to hyaluronate (an allergy) * Medications that could interfere with the planned interventions

What they're measuring

Tegner Activity Level Scale Score

Timeframe: 1 yr postop

Trial details

NCT IDNCT01256788

SponsorThe Hawkins Foundation

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2014-04

Results submitted2016-03-07

View on ClinicalTrials.gov More Meniscus Tear trials