RecruitingNot Applicable

Optical Coherence Tomography Guided Transepithelial Phototherapeutic Keratectomy

United States80 participantsStarted 2011-06

Plain-language summary

Optical Coherence Tomography (OCT) machines are non-contact instruments that can measure the depth of scars and other causes of cloudiness in the front of the cornea. The purpose of this study is to determine whether OCT-guided settings for the lasers used for removal of corneal scars and other partial-thickness corneal defects result in improved vision in patients receiving these procedures.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients with vision primarily limited by superficial opacities and irregularities that could be removed by PTK while leaving at least 250 µm. Exclusion Criteria: * Inability to give informed consent * Inability to maintain stable fixation for OCT imaging * Inability to commit to required visits to complete the study * Deep corneal opacities and irregularities * Cataracts, retinal disease, glaucoma, or other eye conditions that may limit the visual outcome after surgery

What they're measuring

Improvement in best spectacle-corrected visual acuity (BSCVA) after PTK

Timeframe: 12 months post-procedure

Trial details

NCT IDNCT01243931

SponsorOregon Health and Science University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-12

Contact for this trial

Humberto Martinez, COT

503-494-7712 martinhu@ohsu.edu

View on ClinicalTrials.gov More Corneal Opacity trials