CompletedPhase 4

Taurolidine in Haemodialysis Catheter Related Bacteraemia

United Kingdom27 participantsStarted 2010-08

Plain-language summary

The purpose of this study is to determine whether taurolidine with heparin locking solution prevents recurrence of central venous catheter related blood stream infections in haemodialysis patients.

Who can participate

Age range18 Years – 120 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Haemodialysis patients established on dialysis for greater than 90 days who dialyse in-centre at any of the satellite dialysis units of Imperial College Healthcare NHS Trust * All patients with a recent catheter related bacteraemia with an identified organism grown on microbiological culture and treated without catheter removal will be eligible for inclusion. Exclusion Criteria: * Those individuals in whom attempted catheter salvage is clinically not indicated. * Unable to provide informed consent * Known allergy to sodium citrate, heparin or taurolidine. * Bleeding diathesis or physical cause for active bleeding.

What they're measuring

Duration of bacteraemia-free catheter survival

Timeframe: Catheter survival measured up to six months from enrollment date.

Trial details

NCT IDNCT01243710

SponsorImperial College Healthcare NHS Trust

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2012-12

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