Study of the Ability of Betaine Hydrochloride to Increase Stomach Acid in Healthy Volunteers

Inclusion Criteria: * Healthy adult with no active medical problems or significant chronic diseases as determined by the study doctor based on history, physical exam; * BMI between 18.5 - 35 kg/m2; * Taking no medications 2 weeks before and during the study enrollment, including drugs of abuse, prescription or OTC medications (except acetaminophen); * Subjects must be able to maintain adequate birth control during the study independent of hormonal contraceptive use; * Be able to provide written informed consent and comply with requirements of the study; * Avoid eating grapefruit and drinking grapefruit juice from 7 days before the first study day until completion of the entire study; * Abstinence from alcoholic beverages, caffeinated beverages and orange juice from 6pm the night before a study day until completion of that study day; * Fast from food and beverages at least 8 hours prior to the study day; * Be able to read, speak and understand English Exclusion Criteria: * Subjects with a history of gastrointestinal disease including gastroesophageal reflux disease, gastritis, peptic ulcer disease or dyspepsia. * Subjects with a fasting gastric pH of \> 4 (i.e. hypochlorhydria) * Subjects with history of dysphagia, achalasia, or difficulty swallowing capsules, tablets or pills. * Subjects on prescription or chronic over-the counter medications (including hormonal contraceptives); * Subjects with known allergy to study interventions; * Subjects who smoke tobacco; * Subjects …