The purpose of this program of research is to determine whether curcumin, a natural health product, can prevent acute kidney injury and other complications after elective AAA repair. If proven safe and effective, curcumin is an inexpensive intervention which can be readily applied to almost 50,000 AAA repairs performed worldwide each year. New knowledge about this intervention may also guide its use in other surgical and medical settings to prevent complications to the kidneys, heart and other organs.
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Urine IL-18
Timeframe: Post op value
NT-ProBNP
Timeframe: Change in post-operative minus pre-operative plasma NT-Pro BNP
hsCRP
Timeframe: Change in post-operative minus pre-operative plasma hsCRP
Serum creatinine
Timeframe: Change in peak post-operative serum creatinine (umol/L) in the 7 days following AAA repair minus pre-op value