Nasal Tea Tree Oil for the Prevention of Infections in PD Patients

Inclusion Criteria: * Men or women over 18 years of age * A signed and dated written informed consent is obtained prior to participation. * Able to comply with the requirements of the protocol. * Have ESRD and dialysis is planned * Requirement either haemodialysis or peritoneal dialysis Exclusion Criteria: * known sensitivity to TTO * Use of mediated and non-medicated nasal ointments in the past 12 weeks * HD patients likely to transfer to a another dialysis centre in the next 6 months * Re-insertion of CVC * serious, uncontrolled disease (including serious psychological disorders) likely to interfere with the study and/or likely to cause death within the study duration * participation in another clinical trial during the last 12 weeks * previous participation in this trial * known contraindication to any component of mupirocin * concurrent diseases which exclude the administration of therapy as outlined by the study protocol * active infections requiring systemically administered antibiotics or antiviral medications within the last 7 days * acute renal failure * non-compensated heart failure * myocardial infarction during the last 6 months * chronic lung disease with hypoxemia * severe non-compensated hypertension * severe non-compensated diabetes mellitus * known HIV or active chronic hepatitis B or C infection * subjects who, in the opinion of the investigator, are not likely to complete the study for what ever reason. * subjects who, in the opinion of the investigator,…