CompletedNot Applicable

The Foot in Your Nose Study: Links Between Nasal Staphylococcus Aureus Colonies and Diabetic Foot Lesion Infections

France278 participantsStarted 2010-09

Plain-language summary

The presence of S aureus in the nasal passages of diabetic patients may be a risk factor for diabetic foot lesion infections. Our aim is to compare the genetic profiles of S aureus strains found in the noses and on the foot lesions of diabetic patients. The investigators are also studying the virulence of these strains, the prevalance of S aureus at either site, and whether or not the quantity of S aureus found in the nose affects the risk for infection in foot lesions. The investigators also use this study to test the sensitivity and specificity of the GeneXpert system.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Type 1 or 2 diabetic patients * Patients consulting or hospitalized in the Diabetology departments of one of the participating centers * Grade 2-4 ulcer on the foot or ankle (both primo and recurrent events are acceptable) Exclusion Criteria: * Patient refuses to participate * Pregnant, parturient or breastfeeding women * Patient does not have diabetic foot or arteritic * Diabetic ulcer is located elsewhere than the foot or ankle * The ulcer is non-swabbable * Patient does not have social-security coverage * Patient is under any type of guardianship

What they're measuring

Presence/absence of the same S. aureus genetic profile in the nose and on the foot lesion.

Timeframe: 3 hours

Trial details

NCT IDNCT01212120

SponsorCentre Hospitalier Universitaire de Nīmes

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2012-03-19

View on ClinicalTrials.gov More Diabetic Foot trials