CompletedNot Applicable

Post Cond No Reflow

France44 participantsStarted 2009-04

Plain-language summary

After having shown that postconditioning allowed a significant 36% reduction of infarct size as assessed by blood levels of myocardial enzymes in acute myocardial patients, the investigators objective is to assess the effect of postconditioning in acute myocardial infarction (AMI) patients on microvascular obstruction lesions defined by cardiac MRI images.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients \> 18 years old, * Male or female, * Presenting first myocardial infarction, with the beginning of pains \< 12 hours, * Requiring a revascularisation by primary angioplasty or " rescue " (after failure of thrombolysis) on IVA or RCA (not CA). * Artery guilty with TIMI flow = 0 Exclusion Criteria: * cardiac arrest before the angioplasty, * Cardiogenic shock * Occlusion of the artery circumflex responsible for the infarction * Magnetic resonance imaging: contre indication

What they're measuring

Extent of the area of microvascular obstruction

Timeframe: 5 days

Trial details

NCT IDNCT01208727

SponsorHospices Civils de Lyon

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2009-04

View on ClinicalTrials.gov More Myocardial Reperfusion Injury trials