CompletedNot Applicable

The Effects of Amiloride and Spironolactone on Renophysiological and Cardiovascular Variables

Denmark25 participantsStarted 2010-08

Plain-language summary

The investigators wish to study the effect of retaining potassium. The participants have essential hypertension. The test substances are Amiloride, Spironolactone and placebo. The participants will ingest tablets for 28 days before being examined. We will perform a 24 hours urine collection, 24-hours bloodpressure measurement, blood and urine samples and we also examine the patient using a SphygmoCor.

Who can participate

Age range40 Years – 70 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * hypertension, * BMI 18,5-30, * non-smoker Exclusion Criteria: * Smoking * Not using contraceptives * Other illnesses * Drug or alcohol abuse

What they're measuring

Bloodpressure

Timeframe: 24-hours and examination

Trial details

NCT IDNCT01195805

SponsorRegional Hospital Holstebro

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2015-08

View on ClinicalTrials.gov More Essential Hypertension trials