TerminatedNot Applicable

Endothelial Function Study Before Cardiovascular Surgery

France109 participantsStarted 2010-04

Plain-language summary

The aim of this clinical trial is to evaluate the effect of chronic obstructive pulmonary disease (COPD) and/or obstructive sleep apnea syndrome (OSAS) on the endothelial function, before cardiovascular surgery, compared to non COPD non OSAS patients undergoing also a cardiovascular surgery, by an observational physiological study. An interim analysis will be performed when 100 patients will be included.

Who can participate

Age range18 Years – 80 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Men or women between 18 and 80 years old * Patient with planned coronary artery bypass graft surgery * Patient with planned peripheral vascular surgery * Patient with aortic surgery Exclusion Criteria: * Patient with aortic or mitral valvular replacement * Patient with emergency peripheral valvular surgery * Patient with emergency coronary artery bypass graft surgery * Patient with evolutive malignancy disease * Pregnant or lactating women * Patient with inadvisable bronchodilator (used for functional respiratory) exploration

What they're measuring

The primary endpoint is the percent of peripheral arterial tone (PAT) in COPD and/or OSAS patients compared to non COPD non OSAS patients.

Timeframe: one week before their cardiovascular surgery

Trial details

NCT IDNCT01195064

SponsorUniversity Hospital, Grenoble

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2018-11-30

View on ClinicalTrials.gov More Chronic Obstructive Pulmonary Disease (COPD) trials