CompletedNot Applicable

A Trial to Evaluate the Impact of Lung-protective Intervention in Patients Undergoing Esophageal Cancer Surgery

China101 participantsStarted 2010-08

Plain-language summary

The purpose of this trial is to determine whether low tidal volume during intraoperative one-lung ventilation could decrease the incidence rate of postoperative acute lung injury compared to "normal" tidal volume.

Who can participate

Age range18 Years – 80 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * clinical diagnosis of esophageal carcinoma and planned for esophagectomy * indication for one-lung ventilation * informed consent * ASA I\~II Exclusion Criteria: * NYHA III\~IV * severe COPD * pulmonary fibrosis * any new pulmonary infiltrate on chest radiograph * preoperative acute infection suspected * altered liver function( Child-Pugh class B or moe) * acute or chronic renal failure * preoperative corticosteroid treatment during month before inclusion

What they're measuring

cytokines of bronchoalveolar lavage

Timeframe: 10 minutes before surgery ,at the end of surgery immediately

Trial details

NCT IDNCT01194895

SponsorShanghai Zhongshan Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2013-01

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