CompletedNot Applicable

A Study to Identify Differences in Gene Expression in Patients With Bicuspid and Tricuspid Valve Disease

United States91 participantsStarted 2010-06-20

Plain-language summary

For this study, blood and tissue samples will be collected in order to perform genetic testing to help researchers gather information about this disease and how and why it affects some patients more than others.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients \> or = to 18 years of age * Presenting with aortic stenosis and to undergo elective aortic valve replacement or repair with or without aortic aneurysm dilation repair * Able to sign informed consent document Exclusion Criteria: * Patients unable to provide informed consent for any reason * Patients with predominant aortic regurgitation valve disease * Patients with other known connective tissue disorders (such as Marfan's Syndrome, Ehlers-Danlos Syndrome)

What they're measuring

Determine differences in genetic expression profiles using mRNA transcriptional analysis

Timeframe: 12 month

Trial details

NCT IDNCT01194362

SponsorBaylor Research Institute

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2022-09-23

View on ClinicalTrials.gov More Aortic Valve Disease trials