Effect of Calanus Oli on Intra-abdominal Fat, Glucose Tolerance and Lipids in Man (NCT01193543) | Clinical Trial Compass
CompletedPhase 2/3
Effect of Calanus Oli on Intra-abdominal Fat, Glucose Tolerance and Lipids in Man
Norway117 participantsStarted 2010-12
Plain-language summary
Preliminary studies in rats and mice indicate that calanus oil reduce accumulation of intra-abdominal fat. Pilot studies in humans have shown no adverse effects. In the present study 120 subjects, males and females, 20-65 years old, BMI 25-30 kg/m2 will be included and given calanus oli 1 g twice daily versus placebo for 1 year. The hypothesis is that calanus oil will reduce intra-abdominal fat, improve glucose tolerance and lipid profile.
Who can participate
Age range
20 Years – 65 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Body Mass Index (BMI) 25-30 kg/m2
* age 20-65 years
Exclusion Criteria:
* diabetes
* coronary heart disease last 12 months
* unstable angina pectoris
* cancer diagnosed the last 5 years
* use of lipid lowering drugs
* seafood allergy
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial used CT scans to measure intra-abdominal fat — how many CT scans would I have been exposed to during the study, and is that level of radiation something I should think carefully about?
2Calanus oil comes from a marine copepod and isn't a standard prescription treatment — how does the evidence from a completed Phase 2/3 trial like this one compare to what we'd expect from a fully approved medication for managing overweight or metabolic issues?
3Since this trial is completed, have the results been published, and if so, what did they actually show about changes in intra-abdominal fat, blood sugar, and lipids — and do the findings seem strong enough to change how you'd approach my care?
4Before considering something like Calanus oil, would it make more sense to try established lifestyle interventions or medications first, given what's currently known from this trial's results?
5If the trial showed some benefit in reducing intra-abdominal fat, is that the right target for someone in my specific situation, or are there other health markers we should be prioritizing together?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.