Usefulness of High-frequency QRS Analysis in the Evaluation of Patients With Chest Pain (NCT01185899) | Clinical Trial Compass
CompletedNot Applicable
Usefulness of High-frequency QRS Analysis in the Evaluation of Patients With Chest Pain
Israel324 participantsStarted 2010-08
Plain-language summary
Accurate detection of a heart attack (an acute myocardial infarction) is one of the most pressing needs in medicine. Recordings of the electrocardiogram (ECG) (electrical activity of the heart) are one of the first tools used to diagnose a heart attack, but the ECG is not very accurate, especially at the beginning of a heart attack. A new technique for analysing a special part of the ECG may provide more accurate detection of a heart attack. The study hypothesis is that this new technique, the HFQRS analysis, will provide important additional information to that available from the regular ECG.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Patients with chest pain, suspected to have ACS
* Duration of chest pain greater than 20 minutes
* Time from onset of chest pain less than 12h
* Signed an informed consent
Exclusion Criteria:
* History of trauma or any other evident medical cause of chest pain
* Prior coronary artery bypass graft
* Pre-excitation syndrome (example WPW)
* Atrial Fibrillation or significant ventricular arrhythmia
* Bundle branch block, intraventricular conduction delay or
* QRS duration greater than 120 ms
* Implanted pacemaker or defibrillator
* Patients who received fibrinolytic therapy, glycoprotein IIb or IIIa inhibitors before the initial ECG recording
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
diagnosis or rule-out of acute coronary syndrome
Timeframe: diagnosis or rule-out of ACS will be determined at two time points: 1) upon diacharge when discharge diagnosis is determined. Follow up information will be obtained one month post discharge