Stereotactic Body Radiation Therapy (SBRT) in Metastatic Non-small Cell Lung Cancer

Inclusion Criteria: General * Patients with AJCC sixth edition metastatic non-small cell lung carcinoma * Pathologic diagnosis of stage 4 non-small cell lung cancer prior to enrollment. * Patients must have response or stable disease by RECIST criteria after 4 cycles of first-line chemotherapy * Maximum of number of lesions per patient will be 5 total. . * Patients with solitary brain metastases previously treated with surgery or stereotactic radiosurgery (+/- WBRT) and currently controlled at the time of study enrollment are also eligible. Patients with history of brain metastases must have an MRI showing no active brain metastases within 80 days of study enrollment. Patients with a history of brain metastases may have up to 5 extracranial sites of disease except for those with an untreated primary tumor where section 3.1.3.3 will also apply. * Patients with newly diagnosed stage IV NSCLC with an untreated primary must no more than 3 active extracranial metastatic lesions other than the primary site and regional lymph nodes. * Age ≥ 18 years old * Performance Status 0-2 (ECOG) * A signed study specific consent form is required. Lung (only applies to patients with active lung lesions) * Patients cannot have more than 3 lung lesions * Local failure after surgical resection will be consider a metastatic lesion for purposes of protocol inclusion. * All lung lesions must be visible on CT imaging * Cumulative diameter of lung lesions must be \<7cm * Patients may have active me…