A Prospective Study of the Kidney Protective Effect of Aliskiren in Hypertensive Patients With IgA Nephropathy

Inclusion Criteria: * IgA nephropathy confirmed by renal biopsy * Hypertension (\<= 125/75 mmHg) Exclusion Criteria: * Patients who have been treated with angiotensin type 1 receptor blocker or angiotensin-converting enzyme inhibitor within 4 weeks * Severe hypertension (\<= 180/110 mmHg) or secondary hypertension * Patients with history of allergy or adverse effect for aliskiren * Renal dysfunction (estimated Glomerular Filtration Rate \< 60 mL/min/1.73m2) * Pregnancy * Patient treated with cyclosporine * Hyperkalemia (serum potassium \>= 5.6 mmol/L) * Autoimmune disease including systemic lupus erythematosus * Patients inadequate for the study