CompletedNot Applicable

A Pilot Study of a Heparin Dosing Algorithm for Hemodialysis

United States5 participantsStarted 2011-03

Plain-language summary

During hemodialysis treatments, patients receive heparin to prevent clotting. The purpose of this pilot study is to determine if the amount of heparin administered during a patient's hemodialysis can be individualized using an equation for heparin dose adjustment.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Adults 18 years of age or older * Stable hemodialysis prescription prior to study enrollment * Dialyzing through a native fistula or Gore-Tex graft * Blood access must be able to provide a blood flow rate of 400 ml/min Exclusion Criteria: * Non-compliance with dialysis * Hematocrit less than 28% * Active Infection * Diagnosis of Heparin-Induced Thrombocytopenia (HIT)

What they're measuring

Change in dialyzer blood compartment volume when the heparin dose is adjusted using a Robbins-Monro algorithm

Timeframe: up to 8 weeks

Trial details

NCT IDNCT01181544

SponsorVantive Health LLC

Sponsor typeINDUSTRY

Study typeINTERVENTIONAL

Primary completion2011-08

View on ClinicalTrials.gov More Renal Failure Chronic Requiring Hemodialysis trials