RecruitingNot Applicable

Boston Early-Onset Chronic Obstructive Pulmonary Disease (COPD) Study

United States2,000 participantsStarted 1994-07

Plain-language summary

Chronic obstructive pulmonary disease (COPD) is often caused by cigarette smoking, but genetic predisposition also influences COPD susceptibility. The purpose of this study is to identify genetic factors that predispose some individuals to develop COPD.

Who can participate

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria for Early-Onset COPD Probands: * Early onset of COPD in individuals younger than 53 years old * Spirometry results that are indicative of severe COPD (FEV1 \< 40% predicted) * Physician-diagnosed COPD Exclusion Criteria for Early-Onset COPD Probands: * Severe alpha-1 antitrypsin deficiency * Other chronic lung diseases in participants with COPD (except asthma) * Pregnant * Any previous lung surgery including lung transplant or lung reduction volume surgery (LVRS); unless prior Pulmonary Function Tests are available

What they're measuring

No Primary Outcome

Timeframe: Single Visit for approximately two hours to collect study data and samples

Trial details

NCT IDNCT01177618

SponsorBrigham and Women's Hospital

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2027-07

Contact for this trial

Edwin K. Silverman, M.D., Ph.D.

617-525-2128 ed.silverman@channing.harvard.edu

View on ClinicalTrials.gov More Chronic Obstructive Pulmonary Disease trials